俄勒冈州立大学癌症药物研究博士后职位

日期:2015-01-02
A postdoctoral position is available to develop new delivery/targeting systems for cancer treatment. These systems are for parenteral application of a new class of vinca alkaloid drugs designed to target cancer tissue microenvironment.

Job Title: Postdoctoral Scholar-Pharmaceutical Sciences/ Drug Delivery
College: College of Pharmacy
College Website: http://pharmacy.oregonstate.edu
Institution: College of Pharmacy Portland, OR
Position Start Date: Feb-2015
Application Deadline: March, 2015 or until filled

Position Description: A postdoctoral position is available to develop new delivery/targeting systems for cancer treatment. These systems are for parenteral application of a new class of vinca alkaloid drugs designed to target cancer tissue microenvironment. Specifically, this position will be focused on the development and characterization (in vitro and in vivo) liposomal and polymeric micellar formulations culminating in quantifying the pharmacokinetic profile and assessing of the efficacy of these formulations in healthy and cancerous murine models respectively. The research is based on a well-defined project that consists of three stages, first the development of drug formulations, in vitro characterization, and stability. Second, evaluate the anti-tumour efficacy in xenograft and orthotropic murine models. Third, conduct a comprehensive pharmacokinetic study to establish dosing regimen, quantify biodistribution, and model the concentration time profile in blood and the tissue to establish the PK/PD parameters.

Salary is commensurate with education and experience and includes health benefits. The position is for 1 year and can be extended for an additional six months. The position is in the College of Pharmacy-Oregon State University at the Collaborative Life Science Building in Portland, OR.

Minimum qualifications: Ph.D. degree in Pharmaceutical Sciences with focus on drug delivery and formulation with a record of publications in internationally recognized journal.
Preferred qualifications: Familiarity with nanotherapeutics in cancer treatment and a strong background in pharmacokinetics and PK/PD modeling, liposomal formulation and characterization techniques.
Please email a cover letter, CV, complete contact information, and full contact information for 3 references to Adam.Alani@oregonstate.edu

Adam G. Alani, PhD
Assistant Professor of Pharmaceutics
Department of Pharmaceutical Sciences
College of Pharmacy
Oregon State University-Portland Campus at OHSU
2730 SW Moody Ave, CL5CP
Portland Oregon 97201-5042
Tel: (503) 346-4702
Email: Adam.Alani@oregonstate.edu

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