弗吉尼亚州立邦联大学癌症靶向疗法研究博士后职位

日期:2015-01-05
The Faber laboratory focuses on improving and implementing targeted therapies to treat cancers including Head and Neck Lung Breast and Nueroblastoma. We are seeing a postdoctoral Fellow to be involved in NCI-funded work in the fast-growing well-funded VCU Philips Institute for Oral Health Research which is integrated into VCU Massey Cancer Center.

The Faber laboratory focuses on improving and implementing targeted therapies to treat cancers, including Head and Neck, Lung, Breast and Nueroblastoma. We are seeing a postdoctoral Fellow to be involved in NCI-funded work in the fast-growing, well-funded VCU Philips Institute for Oral Health Research which is integrated into VCU Massey Cancer Center.

Responsibilities include: (1) Elucidating the biological mechanisms which lead to depressed BIM levels in oncogene-addicted cancer paradigms. Low BIM expression confers resistance to targeted therapies (for instance, Faber et al. Cancer Discovery 2011). Thus, the goal of this work is to define the mechanisms to which BIM is lowered in these resistant cancers, and to find pharmaceutical ways to de-repress BIM and sensitize these cancers to targeted therapies, with the aim to bring these new combination therapies into the clinic. (2) "Soft" bioinformatic approaches coupled with rigorous pre-clinical testing of novel therapies can lead to new targeted therapies in subsets of cancer (for example, Faber et al. Cancer Discovery 2014). These approaches include testing compounds in patient-derived xenografts and patient-derived cell lines, and this overall approach will be used to find novel targeted therapies in other paradigms.

Qualifications:Knowledge, Skills, Abilities (KSA's) and/or Competencies required to successfully perform work and Education, Experience, Licensure, Certification required for entry into the position.

Familiarity with establishing patient-derived cell lines from surgery or biopsies is a plus. In addition, advanced molecular and cellular biological techniques, such as PCR, cloning, Western blotting, immunoprecipitation, FACS assays including apoptosis and viability. siRNA transections and shRNA infections. Mammalian cell culture. Ability to work as a team and communicate effectively. Must be highly motivated. Ph.D. in cancer biology, biochemistry, microbiology. or a relevant Biological Discipline or equivalent training and experience. Several years experience in biological research setting where patient-derived cell lines are being established is a plus but not neccessary. Ability to work in a diverse environment is required.http://www.massey.vcu.edu/

微信扫一扫分享资讯

相关阅读
加州大学旧金山分校肺癌研究博士后职位
加州大学旧金山分校癌症研究博士后职位
亚利桑那州立大学心理学研究博士后职位
南加州大学免疫学研究博士后职位
福克斯蔡斯癌症中心癌症基因组学研究博士后职位
华盛顿大学医学院泌尿系统研究博士后职位
哪四类求职者最让人反感?

不要做让HR管理者反感的人,要做一个让HR管理者欣赏的人。如果你有以上的坏毛病,一定要改正,因为这些坏毛病会阻碍到你求职,影响到你以后在职场上的发展。

合肥市口腔医院急聘口腔专业博士、硕士

安徽省内唯一一家三级口腔专科医院,创建于1956年,历经六十年的风雨兼程,已发展成为集医、教、研、防为一体的现代化口腔专科医院,并形成了“一院、两区、三部”的格局,现在面向全国急招口腔方面专业人才,欢迎您的投递!

药店筹建招聘 学科呼吸招聘 体检科物理招聘 全科辅导招聘 肛肠科临床招聘 B超文员招聘 儿科导师招聘 麻醉护理招聘 胸外科带头人招聘 医院文秘招聘