The Institute for Cell and Neurobiology is part of the Center for Anatomy at the Charité (http://cbn.charite.de/en/research/groups/wulczyn_cell_fate_decision/). The Institute is home to several independent research groups working in neurobiology with emphasis on molecular development.
We are looking for a highly-qualified post-doctoral candidate to join a DFG financed project as part of SFB 665: Developmental Disturbances in the Nervous System. Our project revolves around post-transcriptional mechanisms guiding neural stem cell behavior in vitro and in vivo (Rybak et al. Nature Cell Biology 2008; Rybak et al., Nature Cell Biology 2009; Rehfeld et al., Cell Tissue Research 2014; Franzoni et al., eLife in press). We combine transgenic mouse and cell culture models to explore the regulatory input and output from the miRNA biogenesis pathway. The ideal candidate will be well-versed in various combinations of 1) embryonic and adult neurogenesis using mouse models, 2) advanced methods for neural differentiation of stem cells including organoid culture, 3) live cell imaging, 4) biochemical characterization of protein-protein and RNA-protein interactions and 4) analysis of ubiquitin-proteasome system activity….