德国生物医学研究所血液癌症研究博士后职位

日期:2015-01-06
A postdoctoral position is available in the laboratory of Dr. Hind Medyouf at the Institute for Tumor Biology and Experimental Therapy Georg-Speyer-Haus Frankfurt Germany

A postdoctoral position is available in the laboratory of Dr. Hind Medyouf at the Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt, Germany.
Dr. Medyouf has a long-standing interest in investigating the molecular mechanisms underlying blood cancers (Medyouf et al., Nat. Med 2007; Blood 2010; JEM 2011; Cell Stem Cell 2014). Her newly established laboratory is more specifically focused on how specific cellular elements and molecular pathways within the bone marrow microenvironment can contribute to the pathogenesis and progression of hematological cancers.

Research Topic:
The proposed project aims to decipher the interplay between hematopoietic and niche cells in the pathogenesis of human myelodysplastic syndromes (MDS), as well as their progression to acute myeloid leukemia or bone marrow failure.
MDS are a heterogeneous group of clonal diseases, mainly affecting the elderly and characterized by ineffective production of mature blood cells, with frequent progression to bone marrow failure (2/3 MDS cases). As such, most MDS patients rely on frequent blood transfusions, a procedure that often results in significant complications. In about 1/3 of MDS cases, the disease progresses to full-blown acute myeloid leukemia, which is particularly difficult to treat. The only potential cure for MDS patients is hematopoietic stem cells (HSC) transplantation, which is limited to younger patients with suitable matching donorshttp://www.nature.com/naturejobs/science/jobs/485931-erc-funded-postdoctoral-position-to-investigate-the-role-of-the-microenvironment-in-leukemias

微信扫一扫分享资讯

乳腺科主治招聘 肿瘤科护理招聘 实验室秘书招聘 康复疼痛招聘 保险推广招聘 发展顾问招聘 后勤影像招聘 教学总监招聘 连锁药业招聘 品牌人员招聘