The University of Gothenburg tackles society's challenges with diverse knowledge. 37 000 students and 6 000 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.
Postdoctoral fellow in pathology and biochemistry
Type of employment: Fixed-term employment, 2 years
Extent: 100 %
Location: Institute of Biomedicine, Gothenburg
First day of employment: March 1 2015
Reference number: PER 2014/550
A postdoctoral position is available at the Institute of Biomedicine, Department of Pathology, in a research group studying etiology and pathogenesis of neuromuscular diseases. The research group has recently identified two new diseases of glycogen metabolism causing progressive muscle weakness and heart failure. These diseases are caused by recessive mutations in the genes encoding the E3-ubiquitin ligase RBCK1 and glycogenin-1, a primer for glycogen synthesis. Both these diseases show a remarkable storage of abnormal glycogen in heart and muscle in addition to various proteins.
pathology and biochemistry
Specific subject description
The research concerns studies on human and mouse muscle tissue in glycogenin and RBCK1 deficiency caused by gene mutations that leads to storage of abnormal glycogen and proteins. The project aims at identifying the storage material to get insights in the pathogenesis by applying proteomic and biochemical studies, cell culturing and immunohistochemistry on material from affected humans and mouse models. Applicants must have good practical skills in mass spectrometry/proteomics/protein chemistry.
Own research under guidance as for a post-doc
An achieved doctoral degree is compulsory for a position as postdoctor at Göteborg University. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application.
Applicants must have good practical and theoretical skills in mass spectrometry/proteomics/protein chemistry. Experience in studies on experimental mouse models is qualifying. Great emphasis is on interpersonal skills and ability to work independently.
For further information please contact:
Anders Oldfors, Professor
+46 31 342 2084
SACO: Catrine Folcker
+46 31 786 2768
OFR/S: Stefan Schedin
+46 31 786 1167
SEKO: Lennart Olsson
+46 31-786 1173
Closing date 2015-01-26
Please apply online; www.gu.s/jobs