Postdoctoral researcher will be working on the project "Role of the stem and differentiated cells in hepatotoxicity and hepatocarcinogenicity induced by cyanotoxins".
The 3-year project (2015-2017) focuses on the role of liver stem and progenitor cells and their differentiation status in the mechanisms of hepatotoxic, tumor promoting and carcinogenic effects of prominent water-born contaminants, cyanobacterial toxins microcystins and cylindrospermopsin. The project aims to investigate changes in expression and activity of specific genes during the hepatic stem and progenitor cell differentiation, and to correlate changes in gene expression with cellular responses to cyanotoxin exposure, in order to understand mechanisms of cyanotoxin-induced disruption of homeostatic balance within a liver tissue.
Required qualifications: Ph.D. (biology, molecular biology, cell physiology, toxicology, pharmacology or similar, Skills and practical experiences in molecular biology techniques for evaluation of gene expression (traditional and real-time PCR, SDS-PAGE and Western blotting, Immunocytochemistry etc), background in in vitro cell culture or other aseptic culture techniques, background in stem cell biology is welcome. We expect independence in planning and realization of research tasks, good communication in English and ability to work in a larger international team.
If interested, send your application including CV to Prof. Ludek Blaha firstname.lastname@example.org ASAP or by January 31, 2015 at the latest