哈尔滨工业大学神经功能障碍研究博士后职位

日期:2015-01-09 点击:
A Postdoc position is available in the laboratory of Dr. Hansruedi Büeler at the Harbin Institute of Technology School of Life Sciences and Technology

A Postdoc position is available in the laboratory of Dr. Hansruedi Büeler at the Harbin Institute of Technology, School of Life Sciences and Technology (http://slst.lhxy.me). Our group studies molecular and cellular mechanisms of neuronal dysfunction in genetically modified cell and animal models of Parkinson’s disease. We investigate triggers and downstream mechanisms of PINK1/Parkin-dependent mitophagy and characterize the role of PINK1 in cell signaling and its potential modulatory function in other neurodegenerative diseases. Translational projects are aimed at developing cell-based assays for PD drug screening and development. Candidates should be experienced in molecular biology and be able to design and perform experiments independently and effectively, with appropriate support. Desired experimental skills include sub-cloning into plasmids, cell culture and transfection of mammalian cells, analysis of mRNA and protein expression, isolation and culture of primary neurons, preparation of cryosections, immunohistochemistry and fluorescence microscopy. Prior experience with animal experimentation and stereotaxic surgery would be advantageous but is not essential. Salary will be according to skills and experience in the areas relevant to the project. For further information please visit http://life.hit.edu.cn/News/Show_e.asp?id=4408. Applications including CV, publication list, description and results of previous research activities and the names and contact details of at least two references should be sent to hbueler@hit.edu.cn until March 9, 2015….

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