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生命科学与技术学院刘冀珑研究组招聘副研究员、助理研究员和博士后

上海科技大学 2017-03-23发布 2017-08-22截止
  • 学历要求: 博士
  • 英语要求: 熟练
  • 年龄要求: 不限
  • 专业要求: 不限
  • 工作年限: 不限
  • 月薪范围: 20000-29999
  • 职位性质: 全职
  • 工作地点: 上海市浦东新区
  • 职称要求: 不限
  • 招聘人数: 1人

职位描述

Long-term positions in Professor Ji-Long Liu’s Group at ShanghaiTechUniversity

http://www.dpag.ox.ac.uk/research/liu-group/liu-group-news/join-us

Research Associate Professor
Research Assistant Professor
Postdoctoral Fellow


Biology of the cytoophidium: an interdisciplinary approach


Professor Ji-Long Liu is relocating his research group from theUniversity of Oxford to ShanghaiTech University, a newly establishedresearch university located at Zhang-Jiang High-Tech Park in Pudong,Shanghai, the “Pharma Valley” of China. We are looking for fourmotivated and enthusiastic scientists to join Professor Ji-Long Liu’sresearch group in Shanghai.


The cytoophidium (plural “cytoophidia”), meaning the cellular snake inGreek, represents a novel type of organelles. In 2010, three groupsincluding us discovered that CTP synthase is compartmentalised into thecytoophidium. Cytoophidia have existed on our planet for at least 3billion years and are evolutionarily conserved from bacteria to human.Using the fruitfly Drosophila melanogaster, the fission yeastSchizosaccharomyces pombe and human cells as prime model systems, wewill study the mechanisms by which metabolic enzymes such as CTPsynthase and IMP dehydrogenase are compartmentalised within a cell. CTPsynthase and IMP dehydrogenase have been attractive targets fordeveloping agents against cancer, virus and parasites. We willinvestigate how various metabolic enzymes are assembled into cytoophidiaand how the cytoophidium and its kind are linked to metabolic regulationand cancer biology.


The post holders will join a highly interactive research team working onmetabolic cell biology. You will develop genetic and biochemicalapproaches to study the biology of the cytoophidium in fruitfly orfission yeast. The study of metabolic compartmentation by genetic andbiochemical approaches promises to form a broad view on basic cellularquestions, as well as sheds light on molecular mechanism of diseaserelated to intracellular compartments.


The successful applicant should have a strong background in genetics,biochemistry and cell biology. Experience of Drosophila or yeastgenetics would be an advantage, although training will be given.Excellent organisational and communication skills will be required,together with the ability to work well within a team.




You will work in the School of Life Science and Technology (SLST) atShanghaiTech University. SLST aims to develop into a world-class,research-oriented school in life science and technology. Additionalinformation about my new lab at ShanghaiTech, click here. My pastresearch at Oxford, click here. Informal enquiries can be made toProfessor Ji-Long Liu at liujl3@shanghaitech.edu.cn


These posts are available from 11 July 2016. They provide opportunitiesto develop research project skills and develop collaborative links withcolleagues within the ShanghaiTech University and elsewhere.


Application Procedure: Submit a cover letter containing the descriptionof the major research achievements, a CV and the names and addresses ofthree individuals who can serve as references toslst@shanghaitech.edu.cn, cc to liujl3@shanghaitech.edu.cn
Review of applications is on a rolling basis with no deadlines, untilall the positions are filled.


Selective References
1. Liu JL. (2016). The cytoophidium and its kind: Filamentation andcompartmentation of metabolic enzymes. Annual Review of Cell andDevelopmental Biology, 32 Epub 27 June 2016. (DOI:10.1146/annurev-cellbio-111315-124907 )
2. Aughey GN, Grice SJ and Liu JL. (2016). The interplay between MYC andCTP synthase in Drosophila. PLOS Genetics 12(2):e1005867.
3. Ghosh S, Tibbit C and Liu JL. (2016). Effective knockdown ofDrosophila long non-coding RNAs by CRISPR interference. Nucleic AcidsResearch 44(9):e84
4. Bassett AR, Tibbit C, Ponting CP and Liu JL. (2013). Highly efficienttargeted mutagenesis of Drosophila with the CRISPR/Cas9 system. CellReports 4(1):220-8.
5. Liu JL. (2010). Intracellular compartmentation of CTP synthase inDrosophila. Journal of Genetics and Genomics 37(5):281-96.
6. Liu JL, Murphy C, Buszczak M, Clatterbuck S, Goodman R and Gall JG.(2006). The Drosophila melanogaster Cajal body. Journal of Cell Biology172(6):875-84.


联系人: 人力资源处

地    址:上海市浦东新区环科路199号

上海科技大学(ShanghaiTechUniversity,简称上科大、ShanghaiTech)是一所由上海市人民政府与中国科学院共同举办、共同建设,由上海市人民政府主管的全日制普通高等学校,2013年9月30日经教育部批准同意正式建立。学校致力于服务国家经济社会发展战略,培养科技创新创业人才,提供科技解决方案及发挥思想库作用,积极投身高等教育改革,努力建设一所小规模、高水平、国际化的研究型、创新型大学。
上科大以理工科为主,设立物质科学与技术学院、生命科学与技术学院、信息科学与技术学院和创业与管理学院等四个学院,实行大学院制,学院下不设系。学校 ...详情

单位概况

上海科技大学
近两周应聘简历处理率:35%
学术/科研
科研院校 其他
1000~9999人
上海市浦东新区环科路199号
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