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生命科学与技术学院刘冀珑研究组招聘副研究员、助理研究员和博士后

上海科技大学 2016-12-09发布 2017-08-22截止
  • 学历要求: 博士
  • 英语要求: 熟练
  • 年龄要求: 不限
  • 专业要求: 不限
  • 工作年限: 不限
  • 月薪范围: 20000-29999
  • 职位性质: 全职
  • 工作地点: 上海市浦东新区
  • 职称要求: 不限
  • 招聘人数: 1人

职位描述

Long-term positions in Professor Ji-Long Liu’s Group at ShanghaiTech University

http://www.dpag.ox.ac.uk/research/liu-group/liu-group-news/join-us

Research Associate Professor
Research Assistant Professor
Postdoctoral Fellow


Biology of the cytoophidium: an interdisciplinary approach


Professor Ji-Long Liu is relocating his research group from the University of Oxford to ShanghaiTech University, a newly established research university located at Zhang-Jiang High-Tech Park in Pudong, Shanghai, the “Pharma Valley” of China. We are looking for four motivated and enthusiastic scientists to join Professor Ji-Long Liu’s research group in Shanghai.


The cytoophidium (plural “cytoophidia”), meaning the cellular snake in Greek, represents a novel type of organelles. In 2010, three groups including us discovered that CTP synthase is compartmentalised into the cytoophidium. Cytoophidia have existed on our planet for at least 3 billion years and are evolutionarily conserved from bacteria to human. Using the fruitfly Drosophila melanogaster, the fission yeast Schizosaccharomyces pombe and human cells as prime model systems, we will study the mechanisms by which metabolic enzymes such as CTP synthase and IMP dehydrogenase are compartmentalised within a cell. CTP synthase and IMP dehydrogenase have been attractive targets for developing agents against cancer, virus and parasites. We will investigate how various metabolic enzymes are assembled into cytoophidia and how the cytoophidium and its kind are linked to metabolic regulation and cancer biology.


The post holders will join a highly interactive research team working on metabolic cell biology. You will develop genetic and biochemical approaches to study the biology of the cytoophidium in fruitfly or fission yeast. The study of metabolic compartmentation by genetic and biochemical approaches promises to form a broad view on basic cellular questions, as well as sheds light on molecular mechanism of disease related to intracellular compartments.


The successful applicant should have a strong background in genetics, biochemistry and cell biology. Experience of Drosophila or yeast genetics would be an advantage, although training will be given. Excellent organisational and communication skills will be required, together with the ability to work well within a team.




You will work in the School of Life Science and Technology (SLST) at ShanghaiTech University. SLST aims to develop into a world-class, research-oriented school in life science and technology. Additional information about my new lab at ShanghaiTech, click here. My past research at Oxford, click here. Informal enquiries can be made to Professor Ji-Long Liu at liujl3@shanghaitech.edu.cn


These posts are available from 11 July 2016. They provide opportunities to develop research project skills and develop collaborative links with colleagues within the ShanghaiTech University and elsewhere.


Application Procedure: Submit a cover letter containing the description of the major research achievements, a CV and the names and addresses of three individuals who can serve as references to slst@shanghaitech.edu.cn, cc to liujl3@shanghaitech.edu.cn
Review of applications is on a rolling basis with no deadlines, until all the positions are filled.


Selective References
1. Liu JL. (2016). The cytoophidium and its kind: Filamentation and compartmentation of metabolic enzymes. Annual Review of Cell and Developmental Biology, 32 Epub 27 June 2016. (DOI: 10.1146/annurev-cellbio-111315-124907 )
2. Aughey GN, Grice SJ and Liu JL. (2016). The interplay between MYC and CTP synthase in Drosophila. PLOS Genetics 12(2):e1005867.
3. Ghosh S, Tibbit C and Liu JL. (2016). Effective knockdown of Drosophila long non-coding RNAs by CRISPR interference. Nucleic Acids Research 44(9):e84
4. Bassett AR, Tibbit C, Ponting CP and Liu JL. (2013). Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system. Cell Reports 4(1):220-8.
5. Liu JL. (2010). Intracellular compartmentation of CTP synthase in Drosophila. Journal of Genetics and Genomics 37(5):281-96.
6. Liu JL, Murphy C, Buszczak M, Clatterbuck S, Goodman R and Gall JG. (2006). The Drosophila melanogaster Cajal body. Journal of Cell Biology 172(6):875-84.


联系人: 人力资源处

地    址:上海市浦东新区环科路199号

上海科技大学(http://www.shanghaitech.edu.cn/)是一所由上海市人民政府与中国科学院共同举办、共同建设的全日制普通公办高等学校,2013年9月30日经教育部批准同意正式建立,现任校长为中科院上海分院院长江绵恒教授。学校将针对我国在能源、材料、环境、人口健康、核心技术等领域所面临的严峻挑战,探索基于创新的解决方案,推动基于创新的生产力发展,为国家和区域转型发展做出实质性贡献。学校位于上海—浦东新区—张江高科技园中区—中科院上海浦东科技园内,与中科院上海高等研究院、国家蛋白质科学中心•上海、中科院上海药物所新药创制平台、上海微小卫星工程中心、上海同步 ...详情

单位概况

上海科技大学
近两周应聘简历处理率:78%
学术/科研
科研院校 其他
1000~9999人
上海市浦东新区环科路199号
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