The Hohenstein laboratory in The Roslin Institute, University of Edinburgh, studies the role of Wt1, ß-catenin and other signal transduction pathways in normal kidney development and Wilms’ tumours. The generation and use of transgenic in vivo models is central in our work. We currently have a vacancy for a post-doctoral scientist on a Roslin Institute-funded position to study integration of signal transduction pathways via chromatin and epigenetic modifications in kidney development in wild-type and Wt1-mutant backgrounds.
We are looking for someone with a strong theoretical background in transcriptional regulation, practical experience in ChIP and other chromatin / epigenetic techniques and who can use these to analyse small samples coming from embryonic kidneys in our mouse models. Funding is available for a maximum of 3 years (depending on starting date) with further extension depending on future funding applications.