Institution
University of California
Position
Postdoc for Biomaterials
Location
Irvine, CA
Date Posted
Sep 13th 2007
Application Deadline
Open Until Filled
Description
An enthusiastic postdoc is invited to join Professor Zhibin Guan’s group to conduct molecular and cell biology studies on newly designed biomaterials. Guan lab has recently developed a new family of safe, versatile and highly functional biomaterials based on saccharide-peptide hybrid copolymers (see the basic design concept in our recent paper: Saccharide-Peptide Hybrid Copolymers as New Biomaterials, Angew. Chem. Int. Ed. 2005, 44, 6529). Currently Guan group is pursuing basic research and potential applications of the new biomaterials in two directions:
(1) develop efficient saccharide-peptide cationic polymers as safe and efficient vectors for delivering small interference RNA (siRNA); (2) develop safe and versatile saccharide-peptide hydrogels for cell culture and tissue regeneration.
The research for the appointed person will involve mammalian cell culture, cytotoxicity assays, gene transfection, and investigation of cell adhesion/proliferation/ differentiation on synthetic extracellular matrices. A Ph.D. with solid background in molecular/cell biology or related area and strong interests in biomaterials and chemical-biology interface is required. Experience with mammalian cell culture and basic cell and molecular biology skills are essential.
Specific skills/experience includes common assays/techniques used in cell biology, quantitative analysis of gene transcription/expression level (real-time PCR, Northern blots, etc), light and fluorescence microscopy and flow cytometry. Prior experience with RNAi and/or biomaterials is highly desirable.
The position is available immediately, supported by a 4-year NIH grant. We offer competitive compensation, exciting research projects, and dynamic interdisciplinary research environment in southern California coastal area. Applications with full CV, research summary and contact information of three references should be sent to zguan@uci.edu. The University of California, Irvine, is an Equal Opportunities Employer.
Contact
Professor Zhibin Guan
Chemistry and Biomedical Engineering
University of California
1102 Natural Sciences II
Irvine, CA 92697-2025
United States
Phone: 9498245172
Fax: 9498242210
Email: guanzb@hotmail.com
Employer's Web Site: http://www.chem.uci.edu/people/faculty/zguan/
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