Institution
Dept of Physics / Dept of Medical Biophysics, University of British Columbia / BC Cancer Research Centre
Position
Postdoctoral Fellowship
Location
UK
Date Posted
Oct 10 2007
Closing Date
15 November 2007
Salary
40000 CAD
Description
A Canadian Institute of Health Reseach (CIHR) funded position is available for a 2 year period. The project involves the development of methods to correlate magnetic resonance (MR) images with histological maps that can be used to assess the effects of drugs on tumour tissue. Tiled image histological mapping (TIHM) - a new tool that permits large regions of tissue to be mapped and probing various features, blood vessels, perfusion, hypoxia, proliferation - will be utilized to guide the development of MR techniques. The ultimate goal is to develop and implement non-invasive MR methods to assess and follow treatment response. Applications in drug development at the mouse model experimental stage as well as the clinical evaluation of drugs are envisaged.
The candidate will draw on expertise in histological mapping by cancer biologist Andrew Minchinton supported by MR physicist Stefan Reinsberg, the candidate will use state-of-the-art animal imaging at 7T in order to develop MR techniques aimed at measuring drug response as well as sophisticated immunohistochemical staining and automated microscopy. Suitable candidates would have experience in tumour biology or MRI.
Contact
Stefan Reinsberg, stefan@phas.ubc.ca.removethis
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