加州圣迭戈Scripps研究所基因组研究博士后岗位

Institution

The Scripps Research Institute

Position

Postdoctoral Fellow

Location

San Diego, CA

Date Posted

Nov 30th 2007

Description

SCRIPPS GENOMIC MEDICINE
A Collaboration of Scripps Health and The Scripps Research Institute

Join a dynamic organization, Scripps Genomic Medicine, an initiative of Scripps Health in collaboration with The

Scripps Research Institute. Our organization supports basic research and clinical programs focused on identifying

and characterizing genes that underlie susceptibility to disease, and taking these findings into drug discovery

programs and ultimately into Clinical trials.

Duties & Responsibilities: A postdoctoral position is available in the newly formed Scripps Genomic Medicine Group.

The goal of our research is to identify and characterize DNA variants associated with human disease, and

application of these discoveries to clinical care. We will perform whole genome association studies using single

nucleotide polymorphism (SNPs) and focused genotyping in targeted regions for replication. We will also conduct

cohort sequencing studies of kilobase-sized intervals in the human genome to gain insight into the allelic

frequency spectrum and structure of DNA variation involved in disease. Additionally, we will perform focused

functional studies to study the biological mechanisms underlying the association between DNA variants and disease.

Primary duties for this position include establishing high-through protocols and targeted functional biological

assays, and analyze data.

Requirements: The individual must be a highly motivated individual with a Ph.D. in Genetics, Molecular Biology or

other related field. Expertise in a broad range of molecular-biological and biochemical techniques (cloning,

sequencing, PCR, purification of DNA, RNA, proteins, etc.) is desirable.

Proficiency in the use of currently existing bioinformatic programs and tools for human DNA sequence analysis,

knowledge of public genomic databases, gene expression analysis, and association study analysis is a plus.

Contact

Please send CV and a list of at least 3 professional references to kfrazer@scripps.edu.