瑞典卡罗琳斯卡研究所分子细胞生物学博士后岗位
InstitutionKarolinska Institutet (http://ki.se/ki/jsp/polopoly.jsp?d=5609&a=11676&cid=5613&l=en)PositionPostdoctoral position in Molecular Cell Biology / Imaging / Cell MigrationLocationSt ...
Institution
Karolinska Institutet (http://ki.se/ki/jsp/polopoly.jsp?d=5609&a=11676&cid=5613&l=en)
Position
Postdoctoral position in Molecular Cell Biology / Imaging / Cell Migration
Location
Stockholm, Sweden
Date Posted
Dec 17th 2007
Deadline
Feb 15th, 2008. (Only candidates selected for interview will receivereply notice.)
Description
POSTDOCTORAL POSITION
Karolinska Institutet
Department of Biosciences and Nutrition
Stockholm, Sweden
Post-doctoral scholarship position available for studies of cellmigration of cancer cells. We are developing a new and unique approachfor fundamental and specific studies of cell migration based on highcontent (quantitative) fluorescent live cell microscopy, which will becombined with RNAi-based screening. For more detailed concepts, see Locket al. below or inquire.
Applicants should preferably have a strong background in live cellfluorescent imaging as well as in cell and molecular biology, andexperiences from RNAi, screening, bioinformatics and Matlab programmingis a plus. A strong dedication and good communication skills in Englishare required. Eligible for this scholarship are foreign citizens whoobtained (or soon will obtain) a PhD outside Sweden within the past 3 years.
Contact
Please submit CV and three letters of reference to Staffan Strömblad,Karolinska Institutet, Department of Biosciences and Nutrition, SE-14157 Huddinge, Sweden.
E-mail:
Staffan.Stromblad@ki.se
Selected recent publications:
Zhang, H., Li, Z., Viklund, E-K. & Strömblad, S. p21-activatedkinase 4 interacts with integrin avb5 and regulates avb5-mediated cellmigration. J. Cell Biol. 158, 1287-1297 (2002).
Zhang, H., Berg, J., Li, Z., Wang, Y., Lång, P., Sousa, A.D., Bhaskar,A., Cheney, R.C. & Strömblad, S. Myosin-X provides a motor-basedlink between integrins and the cytoskeleton. Nature Cell Biol. 6,523-531 (2004).
Bao, W. & Strömblad, S. Integrin av-mediated inactivation of p53controls a MEK-1-dependent melanoma cell survival pathway inthree-dimensional collagen. J. Cell Biol. 167, 745-756. (2004).
Thullberg, M., Gad, A., LeGuyader, S. & Strömblad, S. OncogenicH-Ras V12 promotes anchorage-independent cytokinesis. Proc Natl Acad SciUSA. 104, 20338-20343 (2007).
Lock, J., Wehrle-Haller, B. & Strömblad, S. Cell-Matrix AdhesionComplexes: Master Control Machineries of Cell Migration. Sem. CancerBiol. In press (available on-line) (2007).