英国伦敦学院大学膜蛋白受体信号通路研究博士后岗位
InstitutionUCL The Wolfson Institute for Biomedical Research (http://www.ucl.ac.uk/wibr)PositionPostdoctoral Research AssociateLocationLondon WC1 United KingdomDate PostedFebruary 13th 2008Date Expire ...
Institution
UCL, The Wolfson Institute for Biomedical Research (http://www.ucl.ac.uk/wibr)
Position
Postdoctoral Research Associate
Location
London WC1 United Kingdom
Date Posted
February 13th 2008
Date Expires
February 25th 2008
Description
Project title:
The role of the Mig6 tumour-suppressor in spatio-temporal control ofErbB-receptor signaling.
The successful postholder will work on a project that seeks to provideinsight into the underexplored mechanisms by which a growing family ofmultiadaptor feedback modulators (such as Mig6) contributes to thespecification of receptor tyrosine kinase (RTK) mediated signalingduring tissue development and homeostasis.
The mechanism by which Mig6 negatively regulates ErbB receptor signalingremains unclear and will be the topic of investigation. Morespecifically we will aim at state-of-the-art proteomic identification ofnovel effector molecules that are regulated by Mig6 and characterise therelevance of these interactions for ErbB-regulated cellular anddevelopmental processes.
Applicants should have PhD in a relevant discipline and have thecapacity for carrying out studies independently. Experience of mammaliantissue culture, transfection, molecular biology and protein purificationand characterization would all be advantageous.
The BBSRC funded post is available from 1st of May 2008 for 3 years.
The salary will be on the University scale Grade 7 (£26,666-£32,796)plus £2572 London Allowance. Appointments are usually made to the bottomrange of this scale.
Contact
To apply, please complete a UCL application form and send it by emailto: human.resources@wibr.ucl.ac.uk or by post to:
Mrs. M. Verdon
The Wolfson Institute for Biomedical Research
UCL, Cruciform Building
Gower Street,
London, WC1E 6BT
Tel: 0207 679 6697
CVs received without a UCL application form will not be accepted.
Closing date for applications is 25th February 2008.
Please quote the reference IF 01/08 in all correspondence.
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