波士顿Tufts医学中心分子及细胞信号传导研究博士后岗位
InstitutionTufts Medical Center (http://www.tufts-nemc.org/mcri)PositionPostdoctoral Fellow Molecular Signaling LabLocationBoston MADate PostedMarch 7th 2008Date ExpiresApril 6th 2008Tagspostdoc molec ...
Institution
Tufts Medical Center (http://www.tufts-nemc.org/mcri)
Position
Postdoctoral Fellow, Molecular Signaling Lab
Location
Boston, MA
Date Posted
March 7th 2008
Date Expires
April 6th 2008
Tags
postdoc, molecular signaling, Boston, ma, and usa
Description
A postdoctoral fellow position is available in Dr. Giorgio Lagna’s groupin the Molecular Cardiology Research Institute of Tufts Medical Center,Boston. The lab investigates the action of TGF? and Bone MorphogeneticProteins (BMP) on the cardiovascular system, with special emphasis onthe differentiation of vascular smooth muscle cells. We are particularlyseeking someone to help us elucidate the molecular signaling pathwaysthat specifically direct smooth muscle differentiation, and theenthusiasm to extend these findings to in vivo disease models.
Applicants should have a PhD, MD, or both, with a strong background incell signaling and experience with primary cell culture and in thehandling of mice. Training will emphasize interdisciplinaryrelationships between molecular biology, gene expression, cell signalingand cardiovascular pharmacology and physiology.
Relevant Publications:
1. Lagna G, Ku MM, Nguyen PH, Neuman NA, Davis BN, Hata A. Control ofphenotypic plasticity of smooth muscle cells by bone morphogeneticprotein signaling through the myocardin-related transcription factors.
J Biol Chem. 2007 Dec 21;282(51):37244-55.
2. Lagna G, Nguyen PH, Ni W, Hata A. BMP-dependent activation ofcaspase-9 and caspase-8 mediates apoptosis in pulmonary artery smoothmuscle cells.
Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L1059-67.
3. Lagna G, Hata A, Hemmati-Brivanlou A, Massagué J. Partnership betweenDPC4 and SMAD proteins in TGF-beta signaling pathways.
Nature. 1996 Oct 31;383(6603):832-6.
Contact
Please forward your cover letter and resume to:
Director, Administration and Finance
Molecular Cardiology Research Institute
Tufts-New England Medical Center
750 Washington Street, Box 312
Boston, MA 02111
Or via email to:
dslater@tufts-nemc.org