英国伦敦学院大学肿瘤治疗研究博士后岗位
InsitutionUCL (http://www.ucl.ac.uk)PositionPostdoctoral PositionsLocationLondon UKDate PostedMarch 31th 2008Date ExpiresMay 30th 2008Tagsucl university college london birkbeck college uk cancer postd ...
Insitution
UCL (http://www.ucl.ac.uk)
Position
Postdoctoral Positions
Location
London, UK
Date Posted
March 31th 2008
Date Expires
May 30th 2008
Tags
ucl, university college london, birkbeck college, uk, cancer, postdoc,postdoctoral, crystallography, biophysics, molecualr, chemistry,medicine, and drug discovery
Description
Cancer Research UK funded positions working on new therapies for cancerat Birkbeck College and University College London.
Biophysical Screening/ crystallography
A postdoctoral position is available to work in the laboratory of DrTracey Barrett within the School of Crystallography at Birkbeck College.The applicant should have a strong background in the use of biophysicaltechniques and be expected to work closely with the medicinal chemists.Screening techniques (such as thermofluor and biacore) will be used toscreen for potential ligands of oncoproteins implicated in Karposi’sSarcoma and in the formation of drug resistant tumours in a medium tohigh throughput format. Knowledge of X-ray crystallography and/or NMR ishighly desirable along with protein purification and crystallisationskills. The School of Crystallography at Birkbeck College houses stateof the art facilities for biophysics (installed in a newly refurbished,purpose built laboratory), protein expression/purification and X-raydata collection that will include a CCD detector later on in the year.Informal enquiries should be made to Dr Tracey Barrett at t.barrett@mail.cryst.bbk.ac.uk.
Medicinal chemist/ molecular modeller
A medicinal chemist with an interest in molecular modelling is requiredto work in the laboratory of Dr David Selwood in The Wolfson Institutefor Biomedical Research. Applicants should have a PhD in organicchemistry, some knowledge of molecular modelling and expertise in drugdiscovery would be an advantage. The project involves the design andsynthesis of novel drug candidates for Kaposi’s sarcoma and other commoncancers involves and close collaboration with thecrystallography/screening team. This research will be done in closecollaboration with the group of Prof Chris Boshoff at UCL.
Applicants should be able to work as part of a team and contribute tothe design of drug molecules. The Selwood group undertakes research atthe interface of biology and chemistry.
(http://www.ucl.ac.uk/wibr/research/chemistry/ds/index.htm) The grouphas state of the art medicinal chemistry and modelling facilities.Informal inquiries to d.selwood@ucl.ac.uk.
The above posts are funded for a period of two years in the firstinstance with a view to extension to four depending on progress.
Salary will be on UCL Grade 7 (£26,666-£32,796) + £2572 LondonWeighting. Appointments are normally made to the bottom range of this scale.
Contact
To apply, please complete a UCL application form, available to download at:
http://www.ucl.ac.uk/hr/docs/download_forms/job_app.doc
and email it to: human.resources@wibr.ucl.ac.uk
If you cannot send your application by email, please post it to:
Vacancy DS03/08
The Wolfson Institute for Biomedical Research
Cruciform Building
Gower Street
WC1E 6BT
All applicants must complete a UCL application form in order to be considered.
Unfortunately we cannot write to applicants who are not shortlisted.Consequently, if you have not heard from us within two weeks of theclosing date, please assume that you have been unsuccessful on thisoccasion. We hope that this does not discourage you from making furtherapplications in the future, and would like to thank you for the time youtook to apply for this post.
Closing date for applications is midday, 31 March 2008.