爱丁堡医学研究理事会神经变性疾病博士后岗位

Institution:

MRC (http://www.mrc.ac.uk)

Location:

Edinburgh United Kingdom

Position:

Postdoctoral Career Development Fellow：RNA Editing in Motor Neurone Disease

The closing date for receipt of applications:  28 August 2007

Job Description:

Human Genetics Unit, Edinburgh

Band 4 – ￡24,993 (Pay Award Pending)

An excellent opportunity is available for research on neurodegenerative disease. Decreases in RNA editing in transcripts encoding the dominant AMPA receptor subunit have been reported in Japanese sporadic ALS patients (Nature. 2004 Feb 26; 427(6977) :801).The UK Motor Neurone Disease Association have agreed to fund a two year project to replicate this finding in European cases using spinal cord material from ALS patients stored in the Sheffield Brain and Spinal Cord Tissue Bank. Further studies will investigate mechanisms underlying alterations in RNA editing by examining the expression and interactions of the RNA editing ADAR enzymes in affected motor neurons and in experimental models.

We offer optional membership of the MRC pension scheme and excellent training and development opportunities.

Full details of the position can be found in the job description, which is available at Informal enquiries can be made to Dr. Liam Keegan at Liam.Keegan@hgu.mrc.ac.uk or Dr. Paul Heath at P.Heath@sheffield.ac.uk Applicants should submit a copy of their CV (including publication list if applicable) with their application form.

Contact:

For an application form, please email scotland.recruitment@ssc.mrc.ac.uk or contact 01793 301158, quoting reference number 2007-426/HGU.
For further information about the MRC visit http://www.mrc.ac.uk.