New England Biolabs, Inc. (NEB ) is a privately held biotechnology company with a worldwide reputation for providing quality reagents for the molecular biology market. NEB’s customers range from small academic laboratories to major research institutions to large industrial corporations. NEB has a strong research focus, and relies on the cooperative interaction of a motivated workforce for its success. NEB is located in a beautiful estate setting, LEED certified building north of Boston.

*Postdoctoral Fellowship – Restriction Enzyme Division – Job Code 1042RM *
The Restriction Enzyme Division invites applicants for a postdoctoral fellowship in restriction enzyme engineering. Projects will be part of a basic research program investigating protein-DNA interactions that lead to specific DNA recognition. These projects will involve detailed analysis of sequence-recognition mechanisms through rational protein engineering, and the engineering of restriction endonucleases to achieve altered enzymatic properties. Solid experience in protein biochemistry and structural enzymology is a plus.

The ideal candidate will:
• Have a strong interest in protein engineering, structure and discovery
• Be goal oriented within a team framework with exceptional attention to detail
• Work under the guidance of an established senior scientist
• Be passionate about their research, and display a strong work ethic that emphasizes both efficiency and quality

Qualifications:
• Ph.D in structural molecular biology, biochemistry, or related fields
• Bench experience with molecular cloning, site-directed mutagenesis, protein purification and enzymatic assays
• Experience in structure modeling and familiarity with common structure visualization and manipulation software
• Demonstrate a high level of initiative in performing experiments, analyzing data, performing calculations and drawing conclusions regarding progress and results of work
• Hands-on experience with techniques of X-ray crystallographic structure determination
• Excellent verbal and written communication skills

This position encourages publications in peer-reviewed journals and participation in national and international conferences.

New England Biolabs, Inc. is an equal opportunity/affirmative action employer

Qualified external candidates may apply online at www.neb.com .