英国邓迪大学帕金森氏病研究博士后职位

Grade 7 (£29,249 � £35,938)

Applications are invited for a post-doctoral position to work with Dr Matthias Trost on a joint project with Prof Dario Alessi aimed at studying protein kinases involved in Parkinson’s disease. Recent findings demonstrate that autosomal dominant point mutations within the gene encoding for the Leucine Rich Repeat protein Kinase-2 (LRRK2) predispose humans to develop Parkinson’s disease (PD). Mutations in LRRK2 are frequent, accounting for ~5% of familial PD, and are also found in sporadic PD. Little is known about LRRK2 regulation, its substrates and how mutations cause PD.

We seek a talented and enthusiastic post-doctoral scientist with a background in mass spectrometry, biochemistry, cell biology or a related field. The successful applicant will have an outstanding academic track record and have published at least one first authored paper in an international journal. The candidate will ideally have experience with large-scale proteome and/or phosphoproteome analyses, and knowledge and working experience with mass spectrometry systems and quantitative proteomics as well as the ability to use bioinformatic tools to analyse large-scale data. Knowledge of cell signalling, biochemistry and cell biology would be an advantage, but is not essential. In addition, the candidate should be able to work independently and thrive in a multi-disciplinary research environment. Strong interpersonal and communication skills are essential as is the ability to work as part of a team.

The position is for 3 years and is available immediately, but applicants wishing to start at any time up to 1st January 2013 will be considered.

The Unit’s proteomics facility is equipped with five state-of-the-art mass spectrometers including three Orbitraps, a MALDI TOF UltrafleXtreme and a QTrap 5500. The Unit’s innovative collaboration with the pharmaceutical industry won a Queen’s Anniversary Award for higher education in 2006.

The MRC Protein Phosphorylation Unit is one of world’s leading centres for research on protein kinases and cell signalling and is funded and equipped to the highest international standards. It is based within the College of Life Sciences at the University of Dundee, which has been voted regularly into Europe’s Top10 “Best Place to Work in Academia” in the last annual surveys compiled by The Scientist.

In addition to an excellent scientific environment Dundee offers an affordable standard of living in an area of outstanding natural beauty situated beside the sea and the Highlands of Scotland. According to the British meteorological office Dundee is the UK’s sunniest city.

Please consult the Unit website for further details of its research programmes. ( http://www.ppu.mrc.ac.uk ).

Informal enquiries may be made to Dr Matthias Trost, m.trost@dundee.ac.uk .

How to Apply
To apply on-line please visit: www.dundee.ac.uk/jobs . If you are unable to apply on-line please contact Human Resources on (01382) 386209 (answering machine) for an application pack. Please quote reference number LS0181. Closing date: 10 June 2012.

The University of Dundee is committed to equal opportunities and welcomes applications from all sections of the community.
The University of Dundee is a Scottish Registered Charity, No. SC015096.