法国居里研究所细胞生物学应用于免疫学博士后职位

SENIOR POST -DOCTORAL POSITION AT THE INSTITUT CURIE IN THE CENTER OF PARIS IN CELL BIOLOGY APPLIED TO IMMUNOLOGY

Applicants are invited for a 3-4 year position within a research group led by Dr. Olivier Lantz to work on the cell biology of MR1 restricted antigen presentation to MAIT cells.

In the group, the team studying MAIT cell biology encompasses 6 persons: 1 staff-scientist, 3 post-doc, 1 PhD student, 1 graduate student and 1 technician.

The group is part of a 90-person immunology department headed by S. Amigorena. The lab is located within the Institut Curie campus in the center of Paris. The building is equipped with state of the art facilities (imaging, proteomic, genomic and cytometry). The Institute hosts around 1000 bench scientists including many foreign post-doctoral fellows.

Candidates will have a Ph.D. in immunology or cell biology + first Post-doc. A STRONG EXPERIENCE IN CELL BIOLOGY AND MICROSCOPY TECHNICS IS MANDATORY .
Candidates should have demonstrated success in previous experience in cell biology testified by publications in the field. Solid experience in molecular biology and biochemistry is also required.
High motivation, autonomy and ability to quickly and effectively develop the proposed project in relation with the group leader and collaborators specialized in cell biology will be essential.
Written and spoken English is mandatory.

Please send CV, motivation letter and contact details of at least two persons able to provide references to olivier.lantz@curie.net

References
1. Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells. Dusseaux M, Martin E, Serriari N, Péguillet I, Premel V, Louis D, Milder M, Le Bourhis L, Soudais C, Treiner E, Lantz O. Blood. 2011 Jan 27;117(4):1250-9.
2. L Le Bourhis, E Martin, I Péguillet, A Guihot, N Froux, M Coré, E Levy, M Dusseaux, V Meyssonnier, V Premel, C Ngo, B Riteau, L Duban, D Robert, M Rottman, C Soudais, O Lantz. 2010. Anti-bacterial reactivity of Mucosal Associated Invariant T cells. Nature Immunology 11(8): 701.
3. E Martin, L Duban, E Treiner, L Guerri, H Laude, F. Tilloy, I C. Moura, C Toly, S Cherif, G Vera, A. Devis, V Premel, S Latour, C Soudais, O Lantz. 2009. Stepwise development of human and mouse MAIT cells. PLoS Biology. 10;7(3):e54.
4. Treiner, E., L. Duban, S. Bahram, M. Radosavljevic, V. Wanner, F. Tilloy, P. Affaticati, S. Gilfillan & O.Lantz. 2003. Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature. 342: 164-169.