瑞典卡罗林斯卡研究所再生生物学研究博士后岗位
日期：2008-04-08
来源：丁香人才网
InstitutiolnKarolinska Institute (http://www.dbrm.se)PositionPostdoctoral Scientist in Regeneration BiologyLocationStockholm SwedenDate PostedApril 7th 2008Date ExpiresJune 15th 2008Tagspostdoc regene ...
Institutioln
Karolinska Institute (http://www.dbrm.se)
Position
Postdoctoral Scientist in Regeneration Biology
Location
Stockholm, Sweden
Date Posted
April 7th 2008
Date Expires
June 15th 2008
Tags
postdoc, regeneration biology, regenerative medicine, salamander, stemcell, repair, stockholm, sweden, skeletal muscle, plasticity,neurobiology, and dopamine
Description
A postdoctoral position to study salamander regeneration is available atthe Karolinska Institute, Stockholm, Sweden. Candidates should beexperienced in cell-, molecular-, and developmental biology. Experiencein skeletal muscle biology, neurobiology and training in animal researchare of advantage.
Natural examples of regeneration, such as salamanders, may unravel novelstrategies for cell replacement of damaged or lost tissues. We studyregeneration mechanisms in an aquatic salamander, the newt, which hasthe widest repertoire of regenerative abilities among adult vertebrates.
Our group has two main interests.
The first topic of our research is to understand how skeletal musclecontributes to new tissues during limb regeneration. We have identifieda multipotent stem cell population in salamander skeletal muscle and wetry to understand how these cells take part in limb regeneration.Salamander skeletal muscle may also undergo a unique dedifferentiationprocess during limb regeneration, and we aim to reveal the mechanismsunderlying skeletal muscle dedifferentiation.
The second topic of our research is to reveal how brain regeneration cantake place. Here we focus at neurogenesis/regeneration of adultdopaminergic neurons in a salamander model of Parkinson’s Disease. Therole of GFAP expressing neural stem cells is currently in the focus ofour research and we aim to understand how these are activated in theearly phases of dopaminergic regeneration.
Selected Publications
Parish, C.L., Beljajeva, A., Arenas, E., A. Simon.
Midbrain Dopaminergic Neurogenesis and Behavioral Recovery in aSalamander Lesion-Induced Regeneration Model.
Development, 2007, 134(15):2881-7
Loof, S, Straube, W, Drechsel, D, Tanaka, EM, Simon, A.
Plasticity of mammalian myotubes upon stimulation with athrombin-activated serum factor.
Cell Cycle, 2007, 6(9):1096-101
Morrison JI, Loof S, He P, Alestrom P, Collas P, Simon A.
Targeted gene delivery to differentiated skeletal muscle: A tool tostudy dedifferentiation.
Dev Dyn. 2007 Feb;236(2):481-8.
Morrison, JI, Lööf, S, He, P, Simon A.
Salamander limb regeneration involves the activation of a multipotentskeletal muscle satellite cell population.
J Cell Biol. 2006 Jan 30;172(3):433-40.
Karolinska Institute (http://www.dbrm.se)
Position
Postdoctoral Scientist in Regeneration Biology
Location
Stockholm, Sweden
Date Posted
April 7th 2008
Date Expires
June 15th 2008
Tags
postdoc, regeneration biology, regenerative medicine, salamander, stemcell, repair, stockholm, sweden, skeletal muscle, plasticity,neurobiology, and dopamine
Description
A postdoctoral position to study salamander regeneration is available atthe Karolinska Institute, Stockholm, Sweden. Candidates should beexperienced in cell-, molecular-, and developmental biology. Experiencein skeletal muscle biology, neurobiology and training in animal researchare of advantage.
Natural examples of regeneration, such as salamanders, may unravel novelstrategies for cell replacement of damaged or lost tissues. We studyregeneration mechanisms in an aquatic salamander, the newt, which hasthe widest repertoire of regenerative abilities among adult vertebrates.
Our group has two main interests.
The first topic of our research is to understand how skeletal musclecontributes to new tissues during limb regeneration. We have identifieda multipotent stem cell population in salamander skeletal muscle and wetry to understand how these cells take part in limb regeneration.Salamander skeletal muscle may also undergo a unique dedifferentiationprocess during limb regeneration, and we aim to reveal the mechanismsunderlying skeletal muscle dedifferentiation.
The second topic of our research is to reveal how brain regeneration cantake place. Here we focus at neurogenesis/regeneration of adultdopaminergic neurons in a salamander model of Parkinson’s Disease. Therole of GFAP expressing neural stem cells is currently in the focus ofour research and we aim to understand how these are activated in theearly phases of dopaminergic regeneration.
Selected Publications
Parish, C.L., Beljajeva, A., Arenas, E., A. Simon.
Midbrain Dopaminergic Neurogenesis and Behavioral Recovery in aSalamander Lesion-Induced Regeneration Model.
Development, 2007, 134(15):2881-7
Loof, S, Straube, W, Drechsel, D, Tanaka, EM, Simon, A.
Plasticity of mammalian myotubes upon stimulation with athrombin-activated serum factor.
Cell Cycle, 2007, 6(9):1096-101
Morrison JI, Loof S, He P, Alestrom P, Collas P, Simon A.
Targeted gene delivery to differentiated skeletal muscle: A tool tostudy dedifferentiation.
Dev Dyn. 2007 Feb;236(2):481-8.
Morrison, JI, Lööf, S, He, P, Simon A.
Salamander limb regeneration involves the activation of a multipotentskeletal muscle satellite cell population.
J Cell Biol. 2006 Jan 30;172(3):433-40.
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