爱尔兰国立Maynooth大学免疫学研究博士后岗位
InstitutionNational University of Ireland MaynoothPositionPostdoctoral Fellowship in ImmunologyLocationMaynooth Kildare IrelandDate PostedMay 9th 2008Date ExpiresMay 18th 2008Tagsireland maynooth immu ...
Institution
National University of Ireland Maynooth
Position
Postdoctoral Fellowship in Immunology
Location
Maynooth, Kildare, Ireland
Date Posted
May 9th 2008
Date Expires
May 18th 2008
Tags
ireland, maynooth, immunology, innate immune signalling, arthritis,postdoc, and kildare
Description
Postdoctoral Scientist (Molecular Immunology)
A postdoctoral position funded by Science Foundation Ireland isavailable to study the role of Toll-like receptor 2 and 4 and theinflammatory caspase, caspase-1, in the pathogenesis of RheumatoidArthritis. Toll-like receptors (TLRs) are innate immune receptors thatare activated by pathogens and endogenous ligands, instigatingproinflammatory cytokine production including IL-1beta via caspase-1.Inappropriate activation of TLRs and caspase-1 may give rise to chronicinflammatory disease including Rheumatoid Arthritis (RA). The currentproject will aim to characterise the molecular mechanisms involved inactivating the caspase-1 signalling complexes called ‘inflammasomes’through endogenous and exogenous TLR2/4 ligands.
Applications are sought from highly motivated committed individuals witha PhD in cell biology, biochemistry, immunology or a related discipline.A strong research background in cell signalling and/or molecularimmunology would be advantageous. Expertise in the area of proteomicanalysis (2D gel electrophoresis, DIGE, LC-MS) would be advantageous.
Closing date for applications is Friday 16th May 2008. Review ofapplications will begin immediately and an expected start date not laterthan July 2008 is envisaged. Applicants should submit their CV alongwith the names and contact details of two referees, preferably via email to
Contact
Dr Sinead Miggin
Institute of Immunology
Department of Biology
NUI Maynooth
Co. Kildare
Ireland
Tel: +353-1-708-3855
Fax: +353-1-708 3845
Email: sinead.miggin@nuim.ie
Web: http://immunology.nuim.ie