杜克大学计算生物学和DNA序列研究博士后岗位

日期:2008-06-30 来源:丁香人才网
InstitutionDuke University (http://www.genome.duke.edu/)PositionPostdoctoral Associates in Computational Biology / Regulatory Sequence & Image Expression AnalysisLocationDurham NCDate PostedJune 2 ...
Institution

Duke University (http://www.genome.duke.edu/)

Position

Postdoctoral Associates in Computational Biology / Regulatory Sequence& Image Expression Analysis

Location

Durham, NC

Date Posted

June 26th 2008

Date Expires

August 25th 2008

Tags

postdoc, postdoctoral associate, bioinformatics, computational biology,gene regulation, university, usa, durham, and nc

Description

The research group of Uwe Ohler (Computational Biology of EukaryoticGene Regulation) has two open positions for postdoctoral associates. Weare situated in the Institute for Genome Sciences & Policy at DukeUniversity, and are part of a vibrant community of computational andsystems biology. Ongoing projects are related to the modeling oftranscriptional and post-transcriptional control; evolution ofcis-regulatory regions; and high throughput microscopy and imageexpression analysis.

The focus of the first position is on regulatory sequence analysis andgene expression, and possible projects include analysis and modeling ofpromoter evolution as well as of regulatory networks includingtranscriptional and post-transcriptional control by small RNAs. Abackground in any of genome analysis, expression analysis, and/orevolutionary modeling is a plus, as is experience with machine learning algorithms.

The second position is part of a project [Quantitative modeling ofexpression pattern evolution in insect development] funded by the HumanFrontier Science Program, a collaborative effort with the labs of PavelTomancak at the Max Planck Institute in Dresden/Germany, and CaseyBergman at the University of Manchester/UK. The project aims to link theevolution of gene regulation on the levels of genotype (regulatorysequences) and phenotype (expression patterns obtained by microarrays aswell as 3D microscopy). A background in biomedical image analysis and/orspatial modeling is therefore a strong plus. Alternatively, candidateswith experience in models for comparative regulatory sequence orexpression analysis are encouraged to apply.

Contact

Applicants should have a PhD in computational biology, or in aquantitative discipline (computer science, statistics, physics…) with ademonstrated interest in computational/systems biology. Appointmentswill initially be made for a one-year term, with the possibility ofrenewal. Start date is flexible, but ideally before the end of 2008.Interested applicants should submit a CV and a cover letter statingresearch interests and qualifications (including a copy or link to arepresentative publication). Please feel free to also contact Uweinformally by email if you have any questions.

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