耶鲁大学医学院信号转导博士后
日期：2007-08-08
来源：丁香人才网
耶鲁大学医学院信号转导博士后
Institution
Yale University School of Medicine
Postion
Postdoctoral fellow
Location
New Haven, CT
Date Posted
August 06
Description
Postdoctoral Positions are immediately available to study the mechanismsand function of signal transduction activated by chemoattractants andWnts in the Vascular Biology Program and Department of Pharmacology,Yale University School of Medicine, New Haven, CT.
Chemoattractants play important roles in regulation of the immunefunctions and are key mediators of inflammatory responses. They are alsoinvolved in tumor metastasis. Wnt-activated signaling pathways regulatea wide range of physiological and pathophysiological processes,including embryonic development, organogenesis, bone remodeling,myogenesis, adipogenesis, tumorigenesis, and stem cell biology. We arecurrently using various biochemical, molecular and cell biological,genetic, proteomic, large scale RNAi screening, and transgenic and genetargeting approaches to: 1) characterize signaling pathways and networksof chemoattractants and understand mechanistic basis for chemotaxis ofleukocyte, endothelial cells, and metastatic cancer cells; 2) elucidateWnt signaling mechanisms, investigate the functions of Wnt signalingwith regard to bone, diabetes, and stem cell biology. In addition, weare also exploring the therapeutic and research potentials of smallmolecule compounds we have identified using virtual “in silico”screening for altering Wnt and Dkk activity.
Please see our recent publications and webpage for detail: Nat Genet.37:945, Nat. Cell Biol. 7:399, Mol. Cell Biol. 24:4677, Cell 114:215,New Eng. J. Med. 346;1513, Mol. Cell 7:801, Science 287:1046, PNAS99;3603, EMBO J 18:4233; PNAS 96:10385; JBC 274:30419.
Competitive Salary and excellent work environment are offered.
Contact
Self-motivated individuals with a Ph.D. trained in any area ofbiomedical sciences are encouraged to apply. Send CV and names of threereferences via email to Dr. Dianqing (Dan) Wu (dan.wu@yale.edu).
Yale University School of Medicine
Postion
Postdoctoral fellow
Location
New Haven, CT
Date Posted
August 06
Description
Postdoctoral Positions are immediately available to study the mechanismsand function of signal transduction activated by chemoattractants andWnts in the Vascular Biology Program and Department of Pharmacology,Yale University School of Medicine, New Haven, CT.
Chemoattractants play important roles in regulation of the immunefunctions and are key mediators of inflammatory responses. They are alsoinvolved in tumor metastasis. Wnt-activated signaling pathways regulatea wide range of physiological and pathophysiological processes,including embryonic development, organogenesis, bone remodeling,myogenesis, adipogenesis, tumorigenesis, and stem cell biology. We arecurrently using various biochemical, molecular and cell biological,genetic, proteomic, large scale RNAi screening, and transgenic and genetargeting approaches to: 1) characterize signaling pathways and networksof chemoattractants and understand mechanistic basis for chemotaxis ofleukocyte, endothelial cells, and metastatic cancer cells; 2) elucidateWnt signaling mechanisms, investigate the functions of Wnt signalingwith regard to bone, diabetes, and stem cell biology. In addition, weare also exploring the therapeutic and research potentials of smallmolecule compounds we have identified using virtual “in silico”screening for altering Wnt and Dkk activity.
Please see our recent publications and webpage for detail: Nat Genet.37:945, Nat. Cell Biol. 7:399, Mol. Cell Biol. 24:4677, Cell 114:215,New Eng. J. Med. 346;1513, Mol. Cell 7:801, Science 287:1046, PNAS99;3603, EMBO J 18:4233; PNAS 96:10385; JBC 274:30419.
Competitive Salary and excellent work environment are offered.
Contact
Self-motivated individuals with a Ph.D. trained in any area ofbiomedical sciences are encouraged to apply. Send CV and names of threereferences via email to Dr. Dianqing (Dan) Wu (dan.wu@yale.edu).
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