加拿大蒙特利尔临床研究所免疫系统研究博士后岗位
日期：2007-11-27
来源：丁香人才网
InstitutionInstitut de recherches cliniques de Montreal - IRCM affiliated with Université de Montréal (http://ircm.qc.ca)PositionPost doctoral research fellowLocationMontreal Qc CanadaDa ...
Institution
Institut de recherches cliniques de Montreal - IRCM, affiliated withUniversité de Montréal (http://ircm.qc.ca)
Position
Post doctoral research fellow
Location
Montreal, Qc, Canada
Date Posted
Nov 26th 2007
Description
Post-doctoral research fellow at the IRCM in Montreal
“Alternative splicing in the immune system”
The laboratory “Hematopoiesis and Cancer” at the Institut de RecherchesCliniques de Montreal (IRCM) seeks a highly motivated post-doctoralresearcher at a junior or senior level to work on deciphering thefunction of alternative splicing in the immune system. Of interest to usare in particular the role of the proteins U2AF26, the transcriptionfactor and chromatin modifier Gfi1 and the protein hnRNPL that allimpinge on the alternative splicing of the gene encoding CD45. Thequestions to be solved would be which role these factors play in thedevelopment and activation of immune cells, in particular memoryT-cells, and which target genes are regulated by these factors. Theproject involves using transgenic and gene deficient mice alreadyavailable in the laboratory that over express or lack the genes encodingthese factors.
References:
Heyd et al., Nature Immunology, 2006
Vassen et al., EMBO Journal, 2006
Heyd and Moroy, RNA, 2007
Requirements
Applicants should have a PhD degree in relevant fields of biochemistrymolecular biology and/or immunology and enthusiasm and motivation forbasic biomedical research. Also essential is a strong interest in theregulation of gene expression and alternative splicing in thehematopoietic and immune system. A previous experience with transgenicand knockout mice would be desirable. Good communication skills inEnglish are a prerequisite. Interested applicants should send a coverletter explaining their interests in the project, a curriculum vitaeincluding previous publications and names of three references per Email.
Contact
Information about the IRCM at http://www.ircm.qc.ca/en. Information onour research unit “Hematopoiesis and Cancer” at our website: http://www.ircm.qc.ca/en/recherche/statique/unite45.html
Institut de recherches cliniques de Montreal - IRCM, affiliated withUniversité de Montréal (http://ircm.qc.ca)
Position
Post doctoral research fellow
Location
Montreal, Qc, Canada
Date Posted
Nov 26th 2007
Description
Post-doctoral research fellow at the IRCM in Montreal
“Alternative splicing in the immune system”
The laboratory “Hematopoiesis and Cancer” at the Institut de RecherchesCliniques de Montreal (IRCM) seeks a highly motivated post-doctoralresearcher at a junior or senior level to work on deciphering thefunction of alternative splicing in the immune system. Of interest to usare in particular the role of the proteins U2AF26, the transcriptionfactor and chromatin modifier Gfi1 and the protein hnRNPL that allimpinge on the alternative splicing of the gene encoding CD45. Thequestions to be solved would be which role these factors play in thedevelopment and activation of immune cells, in particular memoryT-cells, and which target genes are regulated by these factors. Theproject involves using transgenic and gene deficient mice alreadyavailable in the laboratory that over express or lack the genes encodingthese factors.
References:
Heyd et al., Nature Immunology, 2006
Vassen et al., EMBO Journal, 2006
Heyd and Moroy, RNA, 2007
Requirements
Applicants should have a PhD degree in relevant fields of biochemistrymolecular biology and/or immunology and enthusiasm and motivation forbasic biomedical research. Also essential is a strong interest in theregulation of gene expression and alternative splicing in thehematopoietic and immune system. A previous experience with transgenicand knockout mice would be desirable. Good communication skills inEnglish are a prerequisite. Interested applicants should send a coverletter explaining their interests in the project, a curriculum vitaeincluding previous publications and names of three references per Email.
Contact
Information about the IRCM at http://www.ircm.qc.ca/en. Information onour research unit “Hematopoiesis and Cancer” at our website: http://www.ircm.qc.ca/en/recherche/statique/unite45.html
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